Tricalcium phosphate 와 gelatin 의 골형성에 관한 비교연구
A Comparateve study of trcalcium phosphate and gelatin on osteogenesis
김학원, 안병후,
소속 상세정보
김학원 ( Kim Hak-Won ) - 조선대학교 치과대학 구강악안면외과학교실
안병후 ( Ahn Byung-Hoo ) - 조선대학교 치과대학 구강악안면외과학교실
KMID : 0353319860100010255
Abstract
This study compared the tissue compatibility and osteogenesis of tricalcium phosphate and gelatin. T112se compounds both incombination and in single were placed in experimentally created defects in the femur of mongrel dogs, and evaluated at 3, 7, 14, 28 and 42 days. Tile histolo, is examination of the implanted tricalcium phoshate and gelatin with their surrounding tissue was revealed as follows:
1. The control group and the tricalcium phosphate group did not show the abnormal tissue reaction in early phase but the gelatin group and the combined group showed th3 retardation of . healing process due to acute inflammatory reaction and foreign body reaction.
2. The cellular organization in the defect area appeared on the 3rd day in the control -roue, thc~ tricalcium phospliate group and the tricalcium phosphate in combined group, but appeared or, the 7th day in the gelatin group.
3. The new bone rmation increased in the tricalcium phosphate group, but it delayed in the gelatin group and the each experimental group showed the retardation of new bone formation than the control group.
4. The tricalcium phosphate group showed the direct ossification and affinity with the new bone but the gelatin group showed the resorption with infiltration of giant cell.
5. The combined group showed the greater retardation of healing process than the control group and the tricalcium phosphate group, but it was of no clinical significance.
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